By Mitch Sabine

Police are seeking public assistance in their search for a 32-year-old Parkwood man who went missing yesterday afternoon.

Police fear the worst for the man, who they say suffers from a medical condition and is prone to becoming disorientated.

He was last seen walking on the Smith Street northern onramp, on the M1 Pacific Motorway, wearing a green t-shirt, khaki coloured camouflage shorts and white runners around 3.30pm.

Police and State Emergency Servie volunteers searched surrounding bushland and residential areas today without success.

Police are urging anyone with information to contact them immediately.